1. Dobrucki LW, Cabrera CL, Bohr DF, and T. Malinski ”Central hypotensive action of clonidine is mediated by nitric oxide” Am J Hypertens 2001; 14(4): 213A
  2. Kalinowski L, Jankowski M, and Dobrucki LW “Nebivolol, a beta 1-selective adrenergic receptor
    antagonist, induces NO-dependent relaxation of renal microvasculature through ATP efflux” FASEB J 2002; 16(5):A1174-A1174
  3. Dobrucki LW, Bohr DF, and T. Malinski “Nitric oxide signaling is involved in the central hypotensive action of moxonidine” FASEB J 2002; 16(4):A113-A114
  4. Mason RP, Jacob RF, Kay RD, Kalinowski L, Madajka M, Dobrucki LW, Malinski T “Synergistic stimulation
    of nitric oxide release from human endothelial cells with amlodipine and atorvastatin” Eur Heart J 2003; 24: 214-214 Suppl. S
  5. Hua J, Bourke BN, Song J, Chow C, Sadeghi MM, Cavaliere P, Hu XY, Jahanshad N, Dobrucki LW, VanRoyen N, Mendizabal M, Buschmann I, Sinusas AJ “Noninvasive detection of angiogenesis, with a technetium-99m labeled peptide targeted at alpha v beta 3 integrin following hindlimb ischemia” J Am Coll Cardiol 2004; 43 (5): 25A-25A Suppl. A
  6. Su HL, Spinale FG, Dobrucki LW, Hua J, Chow C, Sweterlitsch SE, Bourke BN, Cavaliere P, Hu XY, Azure M, Sinusas AJ “Serial targeted radiotracer imaging of matrix metalloproteinase (MMP) activation in a murine model of post-infarction left ventricular remodeling” Circulation 2004; 110 (17): 435-435 2047 Suppl. S
  7. McAteer J, Song JY, Dobrucki LW, Cavaliere P, Dione DP, Hawley C, Hu J, Hendrick JW, McLean JE, Leonardi AH, Weyman C, Liu YH, Spinale FG, Sinusas AJ “Targeted radiotracer imaging of myocardial matrix metalloproteinase activity post-myocardial infarction” Circulation 2005; 112(17): U825-U825 3543 Suppl.S
  8. Sahul Z, Song J, McAteer J, Dobrucki LW, Papademetris X, Duncan JS, Spinale FG, Sinusas AJ “Non-invasive evaluation of regional myocardial strain and activation of matrix metalloproteinases”  J Am Coll Cardiol 2006; 47(4):114A-115A Suppl. A
  9. Sahul Z, Dione DP, Dobrucki L, Kalinowski L, Brennan M, Mekkaoui C, Cavaliere P, Hawley C, Hu X, Haramis H, Evans PM, Weyman C, Liu YH, Madri J, Sinusas AJ “Targeted alpha-v integrin imaging defines spatial and temporal changes in the angiogenic process post myocardial infarction” Circulation 2006; 114(18): 499-499 Suppl.S
  10. Sahul Z, Song J, McAteer J, Dione D, Dobrucki L, Dione DP, Papademetris X, Hawley C, Cavaliere P, McLean J, Duncan J, Spinale F, Sinusas AJ “Quantification of in-vivo matrix metalloproteinase activity and myocardial strain yield unique spatial and temporal patterns in a porcine model of myocardial infarction” Circulation 2006; 114(18): 500-500 Suppl.S
  11. Zhang JS, Ahmed M, Nie L, Asadi A, Dobrucki LW, Esmailzadeh L, Guo XJ, Edwards S, Azure M, Sinusas AJ, Sadeghi MM “In vivo molecular imaging of matrix metalloproteinase activation in vascular remodeling” Circulation 2006; 114(18): 500-500 Suppl.S
  12. Stroud RE, Song J, McAteer J, Sahul Z, Dobrucki LW, Mukherjee R, Dione DP, McLean JE, Leone AM, Hawley C, Bouges S, Cavaliere P, Sinusas AJ, Spinale FG “A matrix metalloproteinase (MMP) targeted radiotracer tracks spatial changes in myocardial MMP-2 activation following myocardial infarction” Circulation 2006; 114(18): 669-669 Suppl.S
  13. Dobrucki LW, Dione DP, Papademetris X, Yu J, Mendizabal M, Sessa WC, Sinusas AJ “Hybrid MicroSPECT/CT Imaging Permits Serial Quantitative Non-invasive Evaluation of Angiogenesis and Arteriogenesis in Murine Model of Hindlimb Ischemia” Mol Imag Biol 2006; 8(2): 62
  14. Dobrucki LW, Dione D, Kalinowski L, Dione D, Papdemetris X, Sinusas AJ “Hybrid microSPECT-CT facilitates quantitative analysis of radiotracer-based images of peripheral angiogenesis” J Nucl Med 2007; 48 (Suppl 2): 166P
  15. Zhang J, Ahmed M, Nie L, Dobrucki LW, Edwards SD, Azure M, Sinusas AJ, Sadeghi M “Imaging injury-induced matrix metalloproteinase (MMP) activation in the vessel wall: J Nucl Med 2007; 48 (Suppl 2): 55P
  16. Liu Y-H, Weyman C, Dione DP, Sahul Z, Dobrucki LW, Brennan M “New method of scatter correction for quantification of molecular targeted cardiac images: canine validation” J Nucl Cardiol 2007; 14: S39
  17. Dobrucki LW, Kalinowski L, Dione DP, Cline G, Mendizabal M, Young LH, Sinusas AJ “Targeted imaging of peripheral angiogenesis in type-1 diabetes demonstrates impairment of alpha-v integrin activation associated with glycation” Diabetes 2007; 56(Suppl 1): A196-A196
  18. Cline GW, Dobrucki LW, Sinusas AJ, Harder J, Muenker C, McLaughlin P “In vivo imaging and biodistribution studies of novel multi-modality nanoparticles for fluorescent and microSPECT imaging” Academy of Molecular Imaging 2007
  19. Dobrucki LW, Tsutsumi Y, Kalinowski L, Dean J, Sen S, Mendizabal M, Aikawa R, Sinusas A “Local IGF-1 gene delivery post myocardial infarction affects temporal and regional alpha-v integrin activation as assessed with radiolabelled RGD peptide” J Nucl Cardiol. 2007; 14(2): S61
  20. Kalinowski L, Sahul Z, Dobrucki LW, Brennan M, Evans P, Haramis H, Madri J, Sinusas AJ “Temporal changes in myocardial uptake of alpha-v integrin targeted tracer correlate with serum markers of collagen turnover and left ventricular function to setting of post-infarct angiogenesis”  J Nucl Cardiol. 2007; 14(2): S62
  21. Weyman C, Dione D, Sahul Z, Dobrucki LW, Kalinowski L, Mekkaui C, Haramis H, Sinusas AJ “Left ventricular dysfunction post myocardial infarction does not alter the biodistribution or clearance kinetics of a targeted radiotracer for imaging angiogenesis” J Nucl Cardiol. 2007; 14(2): S62
  22. Dobrucki LW, Dione D, Kalinowski L, Sinusas AJ. „MicroSPECT-CT Imaging Demonstrates Impairment of Matrix Metalloproteinases Activation in Ischemic Peripheral Angiogenesis in Type-1 Diabetes Associated with Glycation” Circulation. 2008;118:S1012
  23. Hedhli, N., Dobrucki, L.W., Kalinowski, A., Wu, X.H., Sinusas, A.J., and Russell, K.S. 2009. Endothelial Neuregulin Expression is Essential for Angiogenesis in Response to Hindlimb Ischemia. Circulation 120:S1052-S1052.
  24. Nie, L., Razavian, M., Zhang, J., Tavakoli, S., Dobrucki, L.W., Sinusas, A.J., Edwards, D.S., Azure, M., and Sadeghi, M.M. “Imaging Matrix Metalloproteinase Activation to Predict Aneurysm Expansion in Vivo” J Nucl Med 2009; 50:6.
  25. Tsatkin V, Srivastava AV, Liu YH, Dobrucki LW, Sinusas AJ. “A rapid approach for 99mTc-glucarate preparation provides high purity and stability over 4 hours” European Heart Journal Supplements. 2009;11:S76-S76
  26. Zhuang, Z.W., Dobrucki, L.W., Ju, R., Dione, D.P., Deng, Y., Simons, M., and Sinusas, A.J. 2009. Multi-Modality Imaging of Angiogenesis and Arteriogenesis of Swimming-induced Nitric Oxide Protection Against Hindlimb Ischemia. Circulation 120:S361-S361.
  27. Hedhli N, Dobrucki LW, Kalinowski A, Wu X, Sinusas AJ, Russell KS. “Endothelial neuregulin expression is essential for angiogenesis in response to hindlimb ischemia” Circulation. 2009;120:S1052-S1052
  28. Dobrucki L.W., Hawley C.L., Hu J., Sinusas A.J. “Matrix Metalloproteinases Activity is Reduced in Post-mi Myocardium of Diabetic Rats Assessed With Targeted Microspect-CT Imaging” Circulation 2010; 122:A18595
  29. Domagala TB, Szeffler A, Dobrucki LW, Leszczynska-Wiloch M, Kotula-Horowitz K, Szczeklik A, Kalinowski L. Nitric oxide production and endothelium-dependent vasorelaxation induced by 1-methylnicotinamide in human blood vessels. Circulation. 2010;122:A12564
  30. Hedhli N, Dobrucki LW, Kalinowski A, Wu XH, Sinusas AJ, Russell KS. Endothelial specific erbb2 deletion enhances ischemia induced angiogenesis. Circulation. 2010;122:A19312
  31. Zhuang ZW, Dobrucki LW, Dione DP, Simons M, Sinusas AJ. Exercise-induced changes in angiogenesis, arteriogenesis and vascular integrity are enos-no dependent in mice with hindlimb ischemia. Circulation. 2010;122:A21415
  32. Schuelke MR, Dobrucki I, Lapi S, Dobrucki LW. Targeted imaging of myocardial angiogenesis in type-1 diabetes with novel PET radiopharmaceutical demonstrates impairment of alpha-v integrin activation. Diabetes. 2012;61:A124-A125
  33. Dobrucki I, Schuelke MR, Lapi S, Dobrucki LW. Novel 64Cu-labeled targeted agent provides favorable biodistribution, high purity, and stability for pet imaging of angiogenesis. J Nucl Med. 2012;53:28
  34. Li J, Dobrucki LW, Boppart SA “Development of Multimodal Microspheres for Targeted PET and Cerenkov Luminescence Imaging of Cancer” presented at the University of Illinois Cancer Research Forum, March 6, 2012
  35. Kalinowski L, Siekierzycka A, Stepnowska M, Szeffler A, Dobrucki IT, Wojciechowski J, Rogowski J, Dobrucki LW. “Direct Evidence for eNOS-mediated Endothelial Dysfunction in Atherosclerotic Lesions of Human Arteries” European Atherosclerosis Society Congress 2013
  36. Kalinowski L, Stepnowska M, Siekierzycka A, Wozniak M, Szeffler A, Dobrucki LW, Wojciechowski J, Rogowski J, Dobrucki IT. “Uncoupling of eNOS is Related to ADMA Accumulation in the Endothelium Adjacent to Atherosclerotic Lesions” European Atherosclerosis Society Congress 2013
  37. Li J, Dobrucki LW, Marjanovic M, Chaney EJ, Boppart SA “Multimodal Microspheres for Targeted PET and Cerenkov Luminescence-Excited Fluorescence Imaging of Angiogenesis” SPIE 2013
  38. Stepnowska M, Siekierzycka A, Dobrucki IT, Wojciechowski J, Szeffler A, Rogowski J, Dobrucki LW, Kalinowski L “Endothelial Dysfunction in Atherosclerotic Lesions of Human Arteries is associated with eNOS Uncoupling” ESC Congress 2013
  39. Siekierzycka A, Stepnowska M, Dobrucki LW, Wojciechowski J, Wozniak M, Rogowski J, Dobrucki IT, Kalinowski L “Endothelial Dysfunction in Arteries from Patients with Induced Hyperhomocysteinemia Is Associated with eNOS-mediated Nitrooxidative Stress” ESC Congress 2013
  40. Wozniak M, Dobrucki IT, Szeffler A, Stepnowska M, Siekierzycka A, Schuelke MR, Oleksiewicz A, Grossin N, Boulanger E, Schmidt AM, Kalinowski L, Dobrucki LW “PET imaging of receptor for advanced glycation end-products in a murine model of hindlimb ischemia” European Molecular Imaging Meeting 2013
  41. Dobrucki IT, Czerwinski A, Schuelke MR, Wozniak M, Valenzuela F, Sowinski P, Kalinowski L, Dobrucki LW “Synthesis, Characterization, and Biological Evaluation of Novel Dimeric cRGD Peptide for PET Imaging of αvβ3 Integrin Expression” American Peptide Society Meeting 2013
  42. Dobrucki IT, Schuelke MR, Valenzuela F, Czerwinski A, Dobrucki LW. “Evaluation of novel dimeric-cRGD peptide for targeted PET-CT imaging of peripheral angiogenesis in diabetic mice.” J Nucl Med. 2013
  43. Schuelke MR, Dobrucki IT, Caffarini JG, Dobrucki LW “Targeted PET-CT Imaging and Quantification of Myocardial Angiogenesis Demonstrates Altered Alpha-V Integrin Activation in Type-1 Diabetes Mellitus” ASNC 2013
  44. Oleksiewicz A, Dobrucki IT, Schuelke MR, Dobrucki LW “Comparison of Various Image Analysis Techniques to Quantify Peripheral Angiogenesis with Hybrid PET-CT Imaging” ASNC 2013
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