Peer-reviewed articles

  1. Krull A, Frenzel T, Schmidt R, Schwarz R, Dobrucki W, Malys B, Box W, and W. Alberti ”Ein interactives Lernprogramm fuer die Strahlentherapie” Strahlenther. Onkol. 1997; 11:596
  2. Frenzel T, Krull A, Schmidt R, Dobrucki W, Malys B, and W. Box ”Ein Computerlernprogramm fuer die Strahlentherapie” Z. Med Phys 1999; 9:56-59
  3. Brovkovych V, Dobrucki LW, Brovkovych S, Dobrucki I, Nascimento CA, Burewicz A, and T. Malinski ”Nitric oxide release from normal and dysfunctional endothelium” J Physiol Pharmacol 1999; 50(4):575-86
  4. Kidd GA, Dobrucki LW, Brovkovych V, Bohr DF, and T. Malinski ”Nitric oxide deficiency contributes to large cerebral infarct size” Hypertension 2000; 35(5):1111-8
  5. Brovkovych V, Dobrucki LW, Brovkovych S, Dobrucki I, Kalinowski L, Kiechle F, and T. Malinski ”Measurement of nitric oxide during endotoxemia” Ann Clin Lab Sci 2000; 30:321
  6. Dobrucki LW, Kalinowski L, Uracz W, and T. Malinski ”The protective role of nitric oxide in the brain ischemia” J Physiol Pharmacol. 2000; 51(4 Pt 1):695-703
  7. Brovkovych V, Dobrucki LW, Brovkovych S, Dobrucki I, Kalinowski L, Kiechle F, and T. Malinski ”Nitric oxide measurements during endotoxemia” Clin Chem. 2001; 47(6):1068-74
  8. Dobrucki LW, Kalinowski L, Dobrucki IT, and T. Malinski ”Statin-stimulated nitric oxide release from endothelium” Med Sci Monit. 2001; 7(4):622-7
  9. Kalinowski L, Dobrucki LW, and T. Malinski ”Nitric oxide as a second messenger in parathyroid hormone related protein signaling” J. Endocrinol 2001; 170(2):433-40
  10. Dobrucki LW, Cabrera CL, Bohr DF, and T. Malinski ”Central hypotensive action of clonidine requires nitric oxide” Circulation 2001; 104(16):1884-6
  11. Kalinowski L, Dobrucki LW, Brovkovych V, and T. Malinski ”Increased nitric oxide bioavailability in endothelial cells contributes to the pleiotropic effect of cerivastatin” Circulation 2002; 105(8):933-8
  12. Wiemer G, Dobrucki LW, Louka FR, Malinski T, and H. Heitsch “AVE 0991, a nonpeptide mimic of the effects of angiotensin-(1-7) on the endothelium” Hypertension 2002; 40:847-52
  13. Linz W, Itter G, Dobrucki LW, Malinski T, and G. Wiemer “Ramipril improves nitric oxide availability in hypertensive rats with failing hearts after myocardial infarction” J Renin Angiotensin Aldosterone Syst. 2003; 4(3): 180-5
  14. Nanobashvilli J, Neumayer C, Fuegl A, Punz A, Blumer R, Mittlboeck M, Prager M, Dobrucki LW, Huk I, and T. Malinski “Combined L-arginine and antioxidative vitamin treatment mollifies ischemia/reperfusion injury of skeletal muscle” J Vasc Surg 2004; 39(4): 868-77
  15. Hua J, Dobrucki LW, Sadeghi MM, Zhang J, Bourke BN, Cavaliere P, Song J, Chow C, Jahanshad N, van
    Royen N, Madri JA, Mendizabal M, Buschmann I, and Sinusas AJ “Noninvasive Imaging of Angiogenesis
    With a 99mTc-Labeled Peptide Targeted at avb3 Integrin Following Murine Hindlimb Ischemia”
    Circulation 2005; 111(24): 3255-60
  16. Su H, Spinale FG, Dobrucki LW, Song J, Hua J, Sweterlitsch S, Dione DP, Cavaliere P, Chow C, Bourke BN, Hu XY, Azure M, Yalamanchili P, Liu R, Cheesman EH, Robinson S, Edwards DS, Sinusas AJ “Noninvasive targeted imaging of matrix metalloproteinase activation in a murine model of postinfarction remodeling” Circulation 2005; 112 (20):3157-67
  17. Lindsey ML, Escobar GP, Dobrucki LW, Goshorn DK, Bouges S, Mingoia JT, McClister Jr DM, Su H, Gannon J, Macgillivray C, Lee RT, Sinusas AJ, Spinale FG “Matrix Metalloproteinase-9 Gene Deletion Facilitates Angiogenesis Following Myocardial Infarction” Am J Physiol Heart Circ Physiol. 2006; 290(1):H232-H239
  18. Goyal A, Wang Y, Su H, Dobrucki LW, Brennan M, Fong P, Dardik A, Tellides G, Sinusas A, Pober JS, Saltzman WM, Breuer CK “Development of a model system for preliminary evaluation of tissue-engineered vascular conduits” J Pediatr Surg. 2006; 41(4):787-91
  19. Luo D, Luo Y, He Y, Zhang H, Zhang R, Li X, Dobrucki WL, Sinusas AJ, Sessa WC, Min W “Differential functions of tumor necrosis factor receptor 1 and 2 signaling in ischemia-mediated arteriogenesis and angiogenesis” Am J Pathol. 2006 Nov;169(5):1886-98
  20. Kalinowski L, Dobrucki LW, Meoli DF, Dione DP, Sadeghi MM, Madri JA, Sinusas AJ. “Targeted imaging of hypoxia-induced integrin activation in myocardium early after infarction” J Appl Physiol. 2008 May;104(5):1504-12
  21. Zhang J, Nie L, Razavian M, Ahmed M, Dobrucki LW, Asadi A, Edwards DS, Azure M, Sinusas AJ, Sadeghi MM. “Molecular imaging of activated matrix metalloproteinases in vascular remodeling”
    Circulation 2008 ;118(19):1953-60
  22. Dobrucki LW, Dione D, Kalinowski L, Dione D, Mendizabal M, Yu J, Papademetris X, Sessa WC, Sinusas AJ. “SERIAL NON‐INVASIVE TARGETED IMAGING OF PERIPHERAL ANGIOGENESIS: Validation and application of a semi‐automated quantitative approach” J. Nucl Med 2009; 50:1356-1363
  23. Dobrucki LW, Tsutsumi Y, Kalinowski L, Dean J, Gavin M, Sen S, Mendizabal M, Sinusas AJ, Aikawa R. “Analysis of angiogenesis induced by local IGF-1 expression after myocardial infarction using microSPECT-CT imaging.” J Mol Cell Cardiol. 2009 Oct 20
  24. Dobrucki LW, Marsh BJ, Kalinowski L. “Elucidating structure-function relationships from molecule-to-cell-to-tissue: from research modalities to clinical realities.” J Physiol Pharmacol. 2009 Oct;60 Suppl 4:83-93
  25. Dobrucki LW, Meoli DF, Hu J, Sadeghi MM, Sinusas AJ. “Regional hypoxia correlates with the uptake of a radiolabeled targeted marker of angiogenesis in rat model of myocardial hypertrophy and ischemic injury.” J Physiol Pharmacol. 2009 Oct;60 Suppl 4:117-23.
  26. Razavian M, Zhang J, Nie L, Tavakoli S, Razavian N, Dobrucki LW, Sinusas AJ, Edwards DS, Azure M, Sadeghi MM “Molecular Imaging of Matrix Metalloproteinase Activation to Predict Murine Aneurysm Expansion In Vivo” J Nucl Med. 2010 Jul;51(7):1107-1115
  27. Spinale FG, Mukherjee R, Zavadzkas JA, Koval CN, Bouges S, Stroud RE, Dobrucki LW, Sinusas AJ “Cardiac restricted overexpression of membrane type-1 matrix metalloproteinase causes adverse myocardial remodeling following myocardial infarction” J Biol Chem. 2010 Sep 24;285(39):30316-27
  28. Suh JW, Scheinost D, Dione DP, Dobrucki LW, Sinusas AJ, Papademetris X “A non-rigid registration method for serial lower extremity hybrid SPECT/CT imaging” Med Image Anal. 2011 Feb;15(1):96-111
  29. Tavakoli S, Razavian M, Zhang J, Nie L, Marfatia R, Dobrucki LW, Sinusas AJ, Robinson S, Edwards DS, Sadeghi MM “Matrix metalloproteinase activation predicts amelioration of remodeling after dietary modification in injured arteries” Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):102-9
  30. Sahul ZH, Mukherjee R, Song J, McAteer J, Stroud RE, Dione DP, Staib L, Papademetris X, Dobrucki LW, Duncan JS, Spinale FG, Sinusas AJ “Targeted Imaging of the Spatial and Temporal Variation of Matrix Metalloproteinase Activity in Porcine Model of Post-Infarct Remodeling: Relationship to Myocardial Dysfunction” Circ Cardiovasc Imaging. 2011 Apr 19
  31. Hibino N, Villalona G, Pietris N, Duncan DR, Schoffner A, Roh JD, Yi T, Dobrucki LW, Mejias D, Sawh-Martinez R, Harrington JK, Sinusas A, Krause DS, Kyriakides T, Saltzman WM, Pober JS, Shin’oka T, Breuer CK. “Tissue-engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel” FASEB J. 2011 Aug;25(8):2731-9.
  32. Criscione JM, Dobrucki LW, Zhuang ZW, Papademetris X, Simons M, Sinusas AJ, Fahmy TM. “Development and application of a multimodal contrast agent for SPECT/CT hybrid imaging” Bioconjug Chem. 2011 Sep 21;22(9):1784-92.
  33. Razavian M, Tavakoli S, Zhang J, Nie L, Dobrucki LW, Sinusas AJ, Azure M, Robinson S, Sadeghi MM. “Atherosclerosis plaque heterogeneity and response to therapy detected by in vivo molecular imaging of matrix metalloproteinase activation” J Nucl Med. 2011 Nov;52(11):1795-802.
  34. Hedhli N, Dobrucki LW, Kalinowski A, Zhuang ZW, Wu X, Russell RR 3rd, Sinusas AJ, Russell KS. “Endothelial Derived Neuregulin is an Important Mediator of Ischemic Induced Angiogenesis and Arteriogenesis” Cardiovasc Res. 2012; 93(3): 516-24.
  35. Domagala TB, Szeffler A, Dobrucki LW, Dropinski J, Polanski S, Leszczynska-Wiloch M, Kotula-Horowitz K, Wojciechowski J, Wojnowski L, Szczeklik A, Kalinowski L. “Nitric oxide production and endothelium-dependent vasorelaxation ameliorated by N1-methylnicotinamide in human blood vessels” Hypertension 2012 Apr;59(4):825-32
  36. Tang L, Yang X, Dobrucki LW, Chaudhury I, Yin Q, Yao C, Lezmi S, Helferich WG, Fan TM, Cheng J. “Aptamer-functionalized, ultra-small, monodisperse silica nanoconjugates for targeted dual-modal imaging of lymph nodes with metastatic tumors”. Angew Chem Int Ed Engl. 2012 Dec 14;51(51):12721-6
  37. Yin Q, Tong R, Xu Y, Dobrucki LW, Fan TM, Cheng, J. “Drug-Initiated Ring-Opening Polymerization of O-Carboxyanhydrides for the Preparation of Anticancer Drug-Poly-(O-Carboxyanhydride) Nanoconjugates” Biomacromolecules 2013; 14(3): 920-929
  38. Yin Q, Yap FY, Yin L, Ma L, Zhou Q, Dobrucki LW, Fan TM, Gaba RC, Cheng J. “Poly(iohexol) nanoparticles as contrast agents for in vivo X-ray computed tomography imaging” J Am Chem Soc. 2013 Sep 18;135(37):13620-3
  39. Xing H, Tang L, Yang X, Hwang K, Wang W, Yin Q, Wong NY, Dobrucki LW, Yasui N, Katzenellenbogen JA, Helferich WG, Cheng J, Lu Y. “Selective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells in Vitro and in Vivo” J Mater Chem B Mater Biol Med. 2013 Oct 21;1(39):5288-5297
  40. Li S, Sinusas AJ, Dobrucki LW, Liu YH “New approach to quantification of molecularly targeted radiotracer uptake from hybrid cardiac SPECT/CT: methodology and validation.” J Nucl Med. 2013 Dec;54(12):2175-81
  41. Mehra VC, Jackson E, Zhang XM, Jiang XC, Dobrucki LW, Yu J, Bernatchez P, Sinusas AJ, Shulman GI, Sessa WC, Yarovinsky TO, Bender JR. “Ceramide-activated phosphatase mediates Fatty Acid-induced endothelial VEGF resistance and impaired angiogenesis.” Am J Pathol. 2014 May;184(5):1562-76